abstract |
The present invention relates to the use of compounds and compositions of compounds having the ability to inhibit serotonin reuptake and antagonistic, incomplete agonistic or inverse agonistic activity against the 5-HT receptor, for the treatment of depression and other affective disorders. The combined inhibitory effect on serotonin reuptake and the antagonistic, incomplete agonistic or inverse agonistic effect on the 5-HT receptor may belong to one chemical compound or two different chemical compounds. |