abstract |
The present invention relates to conjugates of hydroxyalkyl starch, preferably hydroxyethyl starch, and protein, where these conjugates are formed during the reaction of reductive amination between at least one aldehyde group or keto group, or a group of half acetal hydroxyalkyl starch or a group of hydroxyalkyl starch, or the host group, or the host group, or the host group, or the group of half-acetal hydroxyalkyl starch or a group of hydroxyalkyl starch, or the host group, or the host group, or the group, or the group of half-acetal hydroxyalkyl starch or a group of hydroxyalkyl starch, or the host group, or the host group, or the group, or the group of half-acetal hydroxyalkyl starch or hydroxyalkyl starch, or the host group, or the host group, or the host group, or the group of hydroxyalkyl hydroxyalkyl starch or hydroxyalkyl starch, or the host group, or the host group, or the group, or the group of half-acetal hydroxyalkyl starch or hydroxyalkyl starch; or its derivative is covalently bound to a protein via an azomethine bond or amine bond . The present invention also relates to a method for producing these conjugates and a specific use of the conjugates. |