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filingDate 2008-11-05^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51c912d51b9f1fee74348c6f639bc28d
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publicationDate 2012-11-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EA-017297-B1
titleOfInvention SOME DERIVATIVES 2-PYRAZINONE AND THEIR APPLICATION AS NEUTROFIL ELASTASIS INHIBITORS
abstract The invention provides some new 6-heteroaryl-5-methyl-3-oxo-4- [3- (trifluoromethyl) phenyl] -3,4-dihydropyrazine-2-carboxamide derivatives, their pharmaceutically acceptable salts and their specific forms together with methods their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of human neutrophil elastase.
priorityDate 2007-11-06^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID439242
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID58432788
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3239035
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http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID23778904
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID966
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID451714262
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID300339
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP49151
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID411449242
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403763
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID447811624
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID29256232
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID411454101
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http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419494593
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO77620
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16000
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC3LFK4
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID246227
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO57203
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16545
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID136721
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID103183906
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DB96
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID673473
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO57312
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID21899848
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04985
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCH0ZCS4
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0DB97
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP20391
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16600
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http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID119031

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