| abstract |
This invention relates to new sirtuin modulating compounds and methods for their use. Sirtuin modulating compounds can be used to increase cell lifespan and treat and / or prevent a wide range of diseases or disorders, for example diseases and disorders associated with aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation , malignant disease and / or hot flashes, as well as diseases or disorders in which increased mitochondrial activity will have a positive effect action. Compositions containing a sirtuin modulating compound in combination with another drug are also provided. |