| abstract |
The aim of the invention is a new JAK3 inhibitor, which can be used as a prophylactic and / or therapeutic agent for the prevention and / or treatment of rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjogren's syndrome , Behcet’s disease, type 1 diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn’s disease, asthma, allergic rhinitis and, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia, etc. A pyridine-3-carboxamide derivative represented by the general formula (1) or a salt or solvate thereof. |