| abstract |
The present invention relates to a compound of formula (IIIb) or formula (IVb) or a pharmaceutically acceptable salt thereof, wherein Z is CH or N; Z represents CR or N; Z represents CR or N or its N-oxide; Z represents CH, C (CH) or N, where 0, 1 or 2 of Z, Z and Z are N; R 2 represents a hydrogen atom, methyl, ethyl, i-Pr, amino, hydroxymethyl, CHOME or mono-, di- and trifluoromethyl, NHMe; R 2 represents a hydrogen atom, a halogen atom, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 alkenyl, C 1-6 alkenyloxy, hydroxy, COH, tetrazole, C 1-6 alkoxycarbonyl, cyano, where each alkyl or alkoxy group is unsubstituted or substituted with at most 5 halogen atoms and 0 or 1 additional substituent selected from the group consisting of hydroxy, cyano, tetrazole, C-Salkoxy, COH, C-Salkoxycarbonyl, optionally substituted phenyl, pyridyl, or pyrimidinyl, and where the phenyl is unsubstituted or substituted by 1 or 2 substituents independently selected from halogen atom, hydroxy, methyl, m Toxie and COH; and other meanings are indicated in the claims, and a pharmaceutical composition containing these compounds. |