abstract |
The invention describes a method for stereoselective preparation of compounds of formulas (1A) and (1B) and their salts, primarily their physiologically compatible salts with inorganic or organic acids and bases, possessing valuable pharmacological properties, primarily inhibiting effect on tyrosine kinase-mediated signal transduction, as well as described their use for the treatment of various diseases, especially tumor diseases, as well as benign prostatic hyperplasia, lung and respiratory diseases. |