| abstract |
The invention relates to an antibody and antigen-binding fragment that bind to tau protein in normal human brain tissue and do not bind to tau protein in human brain tissue with AD. In addition, the invention relates to an isolated nucleic acid encoding said antibody and a fragment, to an expression vector, to a host cell, to a method for producing an antibody or a fragment, to a pharmaceutical composition for the treatment of neurodegenerative tautopathies, which contains this antibody or antigen-binding fragment. |