abstract |
Acompoundoftheformula(I):n or a pharmaceutically acceptable ester, amide or salt thereof wherein R, is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methyl-sulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R 2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R 3 is a hydrogen, chlorine or bromine atom or a hydroxyl group; R. is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R, is a hydrogen atom or a methyl group; R 6 is a hydrogen atom or a methyl group; R 7 is a hydrogen atom or a methyl or ethyl group; R 8 is a hydrogen atom or a methyl or ethyl group; X is an oxygen atom or a bond, and Y is an alkylene group of up to 5 carbon atoms, or a bond has been found to possess anti-obesity and/or anti-hyperglycaemic activity. |