http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0103259-B1
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 |
| filingDate | 1983-09-06^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1986-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1986-02-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0103259-B1 |
| titleOfInvention | 4-quinoline derivatives and their preparation |
| abstract | A process for the preparation of mefloquin and its physiologically compatible acid addition salts by reacting 6-phthalimido-1-hexene with a 4-halo-2,8-bis-(trifluoromethyl)-quinoline in the presence of a base, epoxidizing the resulting N-[6-<2,8-bis-(trifluoromethyl)-4-quinolyl>-5-hexenyl]-phthalimide to give N-[4-{3-<2,8-bis-(trifluoromethyl)-4-quinolyl>-2-oxiranyl}-butyl]-phth alimide, treating the latter with hydrazine hydrate and, where applicable, converting the product into an acid addition salt as well as intermediates obtained in this process. |
| priorityDate | 1982-09-10^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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