http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0140784-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3899a93c972ce60b070fca823112248 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D327-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D327-02 |
| filingDate | 1984-10-19^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0f311624a92dda7854e7456b3e53a45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_885ff0ba38a8a9d7f0b231d26cffe4a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae07d8b505602dba02bcd2be0cc1b00 |
| publicationDate | 1985-05-08^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0140784-A2 |
| titleOfInvention | Prostaglandin antagonists |
| abstract | This invention deals with the compounds of the formulae:n whereinn Z is thio, sulfinyl, or sulfonyl; R 1 and R 2 are independently hydrogen, halogen, amino, C 1 to C 4 alkyl, C 1 to C 4 alkylthio, C 1 to C 4 alkoxy, thiol, C, to C 4 alkylsulfinyl, C 1 to C 4 alkylsulfonyl, trifluoromethyl, trifluoromethylthio, cyano, nitro, aralkyl, hydroxyalkyl, C 1 to C 4 alkylamino, dialkylamino wherein each alkyl group has 1 to 4 carbons, or R 1 and R 2 are joined together to form a polymethylene chain of 3 or 4 carbon atoms, with or without a hydroxy or keto functionality; X is O, N-R 3 , wherein R 3 is hydrogen, C 1 to C 4 alkyl, aryl, hydroxy, C 1 to C 4 alkoxy, C 1 to C 5 acyloxy, amino, C 1 to C 4 alkylamino or dialkylamino wherein each alkyl group has 1 to 4 carbons; or a group of the formula:n wherein each Y is independently O or S or NR 6 wherein R 6 is H, C 1 to C 4 alkyl, lower alkanoyl, benzoyl, trifluoroacetyl or CN; and R 4 and R 5 are each independently hydrogen or C 1 to C 4 alkyl and the broken line between R 4 and R 5 represents an optional bond when R 4 and R 5 are not hydrogen; and the pharmaceutically acceptable salts thereof. n These compounds are useful for antagonizing the activity of prostaglandins in a mammal. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0463636-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0463636-A3 |
| priorityDate | 1983-10-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 472 of 472.