| abstract |
Indole-3-carboxamide derivatives of the formula:inclusive of pharmaceutically acceptable acid addition salt and/or hydrate forms thereof, wherein R' is hydrogen, C<sub>1-4</sub> alkyl, phenyl which may be optionally substituted by halogen on the benzene ring or phenyl-C<sub>1-4</sub> alkyl which may be optionally substituted by halogen on the benzene ring; R<sup>2</sup> is hydrogen or C<sub>1-4</sub>, alkyl; R<sup>3</sup> is hydrogen, halogen, C<sub>1-4</sub> alkyl, hydroxy or C<sub>1-4</sub> alkoxy; R<sup>4</sup> is hydrogen, C<sub>1-4</sub> alkyl, C<sub>3-7</sub> cycloalkyl, allyl or benzyl which may be optionally substituted by halogen on the benzene ring or by methyl on the α-carbon; R<sup>5</sup> is hydrogen or C<sub>1-4</sub> alkyl; m is 0 or 1; and n is an integer of 1 to 3, are useful as neuroleptic and anxiolytic drugs, and for the prevention and treatment of psychosomatic disturbances. |