abstract |
A compound of D-phenylalanine derivative for hypoglycemic use, represented by the general formulawherein R<sup>1</sup> is selected from hydrogen, alkyl of 1 to 5 carbon atoms, aryl of 6 to 12 carbon atoms, aralkyl of 6 to 12 carbonand -CH<sub>2</sub>-OCO-C(CH<sub>3</sub>)<sub>3</sub>; R<sup>2</sup> is selected from groups comprising aryl of 6 to 12 carbon atoms, a hetero six-membered ring, a hetero five-membered ring, cycloalkyl, or cycloalkenyl, any of which groups may have one or more substituents; and R<sup>3</sup> is selected from hydrogen and alkyl of 1 to 5 carbon atoms; the salts thereof, and precursors which can be converted thereto in the human or animal body.Some of the compounds are novel per se. |