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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22
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filingDate 1986-08-12^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1989-09-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1989-09-20^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0220805-B1
titleOfInvention Multiphase tablet and process for the preparation thereof
abstract A pharmaceutical composition in the form of a multiphase (especially a bilayered, optionally coated) tablet. The tablet has a narcotic analgesic phase containing a therapeutically effective quantity of a narcotic analgesic or an analgesically effective salt thereof (e.g. codeine phosphate) and a non-steroidal anti-inflammatory phase containing a therapeutically effective quantity of a non-steroidal anti-inflammatory carboxylic acid or an anti-inflammatory salt or ester thereof (e.g. ibuprofen). The narcotic analgesic phase is free from a non-steroidal anti-inflammatory carboxylic acid or salt or ester thereof, stearic acid and a.stearate salt, and the non-steroidal anti-inflammatory phase is free from a narcotic analgesic or salt thereof, stearic acid and a stearate salt. Further, both the narcotic analgesic phase and the non-steroidal anti-inflammatory phase contain a self-lubricating, compression aid, especially a self-lubricating, direct compression aid, such as microcrystalline cellulose.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011121160-A1
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8226979-B2
priorityDate 1985-08-28^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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