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filingDate 1989-03-28^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b2b0f2ee36d4b321d07909e21bf9ff5
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publicationDate 1989-10-04^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0335308-A2
titleOfInvention Protein non-adsorptive polyurea-urethane polymer coated devices
abstract Polymer-coated medical and laboratory devices are disclosed which are characterized by their biocompatibility and resistance to nonspecific protein adsorption. At least 75%, preferably at least 90%, of the prepolymers from which the polymer coatings are prepared are isocyanate-capped oxyethylene-based diols or polyols having molecular weight of about 7000-30,000. Essentially all of the hydroxyl groups of the diols or polyols are capped with polyisocyanate prior to formation of the hydrated polymer coating.
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