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filingDate 1989-08-18^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1991-10-30^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0355737-A3
titleOfInvention Expression of functional homologous and heterologous proteins on the outer membrane of e.coli and other gram-negative bacteria
abstract The invention relates to fusion proteins with the outernMembrane protein A (OmpA) gram negative bacteria and verndrive to the expression of homologous and heterologous proteinsnon the outer membrane of E.coli and other gramnegatinven bacteria. The protein to be expressednin the form of their cDNA in the outer membrane protein An(OmpA) in the area of the codons of one of the four outernVertices of this protein are inserted. Farthernthese proteins can also be added theren"Stalk" are used, which from the amino and carnboxyterminus of the hemagglutinin molecule from influenzanVirus is formed and in turn in one of the ompAnVertices are inserted. The fusion proteins willnexpressed in the bacteria in a controlled manner.
priorityDate 1988-08-24^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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