| abstract |
There is provided the use of a compound of formula I in the preparation of a medicament for use in the prevention or treatment of neurological disorders,n wherein, nAr₁ and Ar₂, which may be the same or different, independently represent phenyl substituted by one or more of amino, nitro chlorine, bromine, hydroxy, C1 to 6 alkoxy, C1 to 6 alkyl or cyano; in addition one of Ar₁ or Ar₂ may also represent phenyl; nR₁ represents hydrogen or C1 to 6 alkyl; nR₂ represents hydrogen or COCH₂NH₂; nR₃ represents hydrogen or C1 to 6 alkyl; nprovided that when R₂ represents hydrogen, then one or both of Ar₁ and Ar₂ may also represent phenyl, fluorophenyl or 2-, 3- or 4- pyridinyl and R₁ may also represent C1 to 6 alkoxycarbonyl or trifluoromethyl; nor a pharmaceutically acceptable salt thereof. n Some of the compounds of formula I are novel, and there are provided processes for making these, together with processes for making pharmaceutical compositions containing the novel compounds. |