| abstract |
A renin inhibiting compound of the formula:n wherein A is a substituent; R 1 is hydrogen, loweralkyl, substituted loweralkyl or loweralkenyl; X is CH 2 , CHOH, C(O), O, S, S(O), S0 2 , NH, N(O) or -P(O)O-; R 3 is loweralkyl, loweralkenyl or substituted loweralkyl; and T is mimic of the Leu-Val cleavage site of angiotensinogen; or a pharmaceutically acceptable salt, ester or prodrug thereof. |