http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0376218-A3
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C311-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-708 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-02 |
filingDate | 1989-12-22^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1991-11-13^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0376218-A3 |
titleOfInvention | Racemization free attachment of amino acids to solid phase |
abstract | This invention pertains to amino acids attached nto a solid support in a racemization free manner and nto a method of covalently linking amino acids to solid nsupports for use in solid phase peptide syntheses, through na compound of the formula: n nwherein Z is an Nα protecting group; nB is one or more amino acids having protected or nunprotected side chains; nR₁ and R₂ are the same or different and are nselected from the group consisting of hydrogen, a nlinear or branched, saturated or unsaturated nalkyl, aryl and benzyl; nA is a substituted or unsubstituted aromatic nring; nY is a hydrocarbon chain having a linear or nbranched, saturated or unsaturated alkyl, aryl or naralkyl which may be linked to A through an ether nlinkage; nD is an oxygen or -NH- which may be linked to a nspacer selected from the group consisting of one nor more natural and unnatural amino acids or nhydrocarbon chain having a linear or branched, nsaturated or unsaturated alkyl, aryl or aralkyl ngroup, the spacer being linked to the carbonyl nthrough an oxygen or -NH- linkage; and nSS is a solid support which is bound to the ncarbonyl group through D. |
priorityDate | 1988-12-27^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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