Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_da5ac784fcbb213313bda68dda9907b4 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate |
1988-09-09^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62bac2c7d7287ec8f7915cd57d39c843 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb0bd6709efa5bd97b79ae0488bbe288 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b9537b59a0c7f41364cfa8ff9484a17 |
publicationDate |
1990-10-24^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0393045-A1 |
titleOfInvention |
Fv antibody fragment production |
abstract |
A process for the production of a polypeptide comprising direct expression of the polypeptide in bacterial host cells characterised in that an inducible expression system is used in combination with a protease deficient bacterial host system. The process is particularly useful for the production of small polypeptides especially immunologically functional antibody fragments and in particular heavy and light chain polypeptides comprising complementary variable domains. Further aspects of the invention relate to suitable expression vectors and bacterial host systems. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6358710-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674164-B2 |
priorityDate |
1987-09-09^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |