http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0487718-A1

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filingDate 1991-06-05^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd5a39ab8bf61fd3bd04b20f8c44d8d4
publicationDate 1992-06-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0487718-A1
titleOfInvention NUCLEIC ACID PROBES with negatively charged haptens which are attached to the probe via a hydrazine binding moiety
abstract The nucleic acid probe presented comprises a probe polynucleotide, a charged hapten marker and a binding moiety. The protein probe includes a probe protein, a charged hapten tag and a binding moiety. The charged hapten label joined to the linker moiety may include a negatively charged sulfophenylhydrazine labeling compound. Polyclonal antibodies and monoclonal antibodies having a specific affinity for the charged hapten markers are presented as well as hybridomas which can constitute the monoclonal antibodies. The invention also provides methods and kits for constituting the nucleic acid probes, for constituting the protein probes, for detecting a nucleic acid probe capture polynucleotide and for detecting a protein probe capture molecule.
priorityDate 1990-06-20^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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