http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0488965-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c646f75c4f7c6349f35c8fe01934921 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-88 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-88 |
filingDate | 1991-11-19^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6265decda0fdb6cc459ebeef59e60aa |
publicationDate | 1992-06-03^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-0488965-A1 |
titleOfInvention | Phthalidilidene derivatives of carnitine and alkanoylcarnitines and pharmaceutical compositions containing them |
abstract | (3-phtalidylidene) alkyl esters of carnitine and alkanoyl carnitines of general formula (I)n n wherein n Y is a C₁-C₅ alkylene group, unsubstituted or substituted with one or more lower C₁-C₄ alkyl groups; n R is hydrogen or C₂-C₆ alkanoyl; n R₁, R₂,R₃, and R₄, identical or different, are hydrogen, halogen C₁-C₈ alkoxy, C₁-C₄ lower alkyl, halogen-substituted lower alkyl, amino, alkyl-substituted amino wherein the alkyl group has 1 to 4 carbon atoms, nitro, cyano, C₁-C₄ alkanoylamino, or R₁ and R₂ taken together, R₂ and R₃ taken together or R₃ and R₄ taken together form a C₁-C₄ alkylenedioxy group, and X⁻ is the anion of a pharmacologically acceptable salt are potent PAF (plateletactivating factor) and acetyl-cholinesterase antagonists. n Pharmaceutical compositions containing the compounds of formula (I) are useful for the therapeutical treatment of inflammatory and allergic conditions, particularly asthma, anaphylactic shock, as contraceptives and for the treatment of pre-senile and senile dementias (typically, Alzheimer's disease). |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0634392-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0706793-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0706793-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9500157-A1 |
priorityDate | 1990-11-20^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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