Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e7b522b71fd001f1a633fd8563b2a3e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-02 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-163 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 |
filingDate |
1991-07-10^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
1998-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7e9068785293f6b4939a7448c3a349e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d71bb95d7e250eb9231f9e20910816f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f0c13f58bb8751161039f386ff8ea57 |
publicationDate |
1998-12-30^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-0491057-B1 |
titleOfInvention |
Hybridoma which produces avian specific immunoglobulin g |
abstract |
A thymidine kinase deficient established fused cell comprising an avian B lymphoblast and an immune avian splenic cell fused thereto and being capable of expressing an immunoglobulin; a process for producing said fused cell which comprises mutating an avian B lymphoblast cell line, separating a thymidine kinase deficient cell by using a medium containing a thymidine analog, fusing an immune avian splenic cell to the separated cell, mutating the fused cell thus obtained, and separating a thymidine kinase deficient fused cell by using a medium containing a thymidine analog; an IgG producing fused cell comprising the aforementioned established fused cell and an antigen-immunized avian splenic cell further fused thereto; and a process for producing an avian IgG by culturing the IgG producing fused cell in a medium. The antibody producing cell of the invention can produce an avian IgG stably over a long period of time, so that it becomes possible to mass-produce an avian IgG. <IMAGE> |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014093908-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11111314-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2336329-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2044839-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10881085-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015143414-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10787522-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3895528-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018136823-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2602323-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9476027-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10954310-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3382022-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020132557-A1 |
priorityDate |
1990-07-10^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |