| abstract |
The invention relates to methods of activating polymeric supports and organic ligands of covalent bond with said activated polymeric supports, a new class of products thus prepared as well as the use of these products in order to separate and purify organic compositions, especially those of biochemical interest. In one of these aspects, the invention relates to a method of activating polymer gels and organic ligands of covalent bond containing one or more nucleophilic groups such as amino, hydroxyl or sulphydryl groups, to said activated polymer gels. In other aspects, the invention relates to methods and compositions for the purification and recovery of specific organic molecules of biological interest, and in particular proteins such as immunoglobulins, by the use of a protein A mimic ligand. and / or non-peptido protein G (that is to say an immunoglobulin binding ligand) linked to a polymer gel, as well as methods for preparing said protein A and / or non-protein G mimic ligands -peptido through activated polymers. |