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filingDate 1990-10-12^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2007-10-03^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d842c2f591a85e35d8be338529de598e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a56cd4a6e83640cd58d4c1fb54d81e5c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be47faf16412caff1a1391ee264a770b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cce105a1e227d73e3f0b524cb0c9ab8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7082e8c65f61c7c728d9036d043bb716
publicationDate 2007-10-03^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0497828-B2
titleOfInvention A process for endoproteolytically processing (precursor) proteins and for the (micro)biological production of proteins
abstract The invention is based on the finding that furin belongs to a family of endoproteolytically active enzymes and relates to a process for the in vitro cleavage of a protein by treating the protein in the presence of Ca<2+> ions with furin or a furin-like enzyme, or an endoproteolytically active fragment, derivative or fusion protein of furin or furin-like enzyme. The invention can be used for the (micro)biological production of a protein by culturing genetically engineered cells expressing a pro-form of the protein as well as furin or a furin-like enzyme and isolating the protein formed.
priorityDate 1989-10-25^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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