| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9f5dcaa66a256cde1fe61ccfd7d6d641
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_678317f7d7e5cb57e28d1a9fa71aa72a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c01a4bc0a08bc17d5713a52fe23ae28 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-0207
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-001 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-02 |
| filingDate |
1991-06-14^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f521c652587650f64dad9a8c3baf456
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d94447edddb033ff736e1b4d4d0326ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01d7ae14be06decf2ccf6f40dc812b16 |
| publicationDate |
1993-04-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0535155-A1 |
| titleOfInvention |
Libraries of modified peptides with protease resistance |
| abstract |
Polymeric peptides composed of monomeric units in which the monomeric units include at least a few substitute amino acids and can include conventional amino acids. Peptoids can be synthesized in large numbers to produce libraries of peptoids that can be sorted to isolate peptides with the desired biological activity. Some peptoids are designed to mimic as closely as possible the activity of known proteins. Other peptoids are designed to have higher or lower activity than known proteins, and they can be designed to block known receptor sites and / or highlight a desired immunogenic response and therefore act as vaccines. A range of different amino acid substitutes is described, as well as their methods of synthesis and methods of using said amino acid substitutes in the synthesis of peptoids and peptoid banks. The invention also relates to methods of screening libraries to obtain the desired peptoids exhibiting particular biological activity. The peptoids are preferably linked to a pharmaceutically active drug forming a conjugate having an increased binding affinity to a particular biological receptor site. |
| priorityDate |
1990-06-14^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |