http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0664307-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_45a7093422004bf6e0e2ff17041fbb60 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-4808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G18-283 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-7023 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G18-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 |
| filingDate | 1994-07-29^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ba290f3f36d6d10d82f2491f95883c2 |
| publicationDate | 1995-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0664307-A1 |
| titleOfInvention | Base polymer for percutaneously absorbable preparation |
| abstract | A base polymer for percutaneously absorbable preparations that is solid at ordinary temperatures but turns into a low-viscosity liquid near the human skin temperature, contains a hydrophilic segment, is responsive to heat and water, and enables drugs which have been difficult to compound into a percutaneously absorbable preparation to be stored stably for long and absorbed percutaneously with a high releasability and a high sustained releasability without causing much skin stimulation. The polymer comprises a heat-responsive segmented polyurethane represented by the general formula R-A-(U)-C-(U)-B-R¹, wherein A and B represent each independently a polymer of ethylene oxide, propylene oxide, tetramethylene oxide or 1,2-butylene oxide, or a random or block copolymer thereof; R and R¹ represent each H, CH₃, C₂H₅, C₃H₇ or C₄H₉ as the terminal group of A and B, respectively; C represents a residue of a diisocyanate compound; and (U) represents a urethane linkage; and wherein at least one of A and B is hydrophilic and at the same time will melt near the human skin temperature. |
| priorityDate | 1993-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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