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filingDate 1995-07-11^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8abd9396d96cd878d9333d870e80be2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c1db1c79eaaf0f0fdaf631e0dd03bb4
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_831502f57fce6d8edcc9795f82d773df
publicationDate 1996-01-17^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0692478-A1
titleOfInvention Process for the preparation of optically active 4 substituted (S)-2-oxazolidinone, optically active (S)-aminoalcohols and utilization of there compounds
abstract 2.1. Process for the preparation of optically active, 4-substituted (S) -2-oxazolidinones of the general formula (IV) where R stands for a space-filling, branched, at least one tertiary carbon atom-containing alkyl group with 5 - 10 carbon atoms has not been disclosed to date.n n n 2.2. The fact that an optically active (S) -amino alcohol of the general formula (III) in which R represents a bulky, branched alkyl group containing at least one tertiary carbon atom and having 5 to 10 carbon atoms, acylated with a chloroformate on nitrogen and the intermediate with a catalytic effective amount of a base is cyclized to the corresponding (S) -2-oxazolidinone of the formula (IV), the desired products can be prepared in high purity and good yield. Compounds of the formulas (III) and (IV) are new.n n n 2.3. Pharmaceutical intermediates, asymmetric synthesis.
priorityDate 1994-07-15^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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