abstract |
PCT No. PCT/GB94/01610 Sec. 371 Date Apr. 19, 1996 Sec. 102(e) Date Apr. 19, 1996 PCT Filed Jul. 27, 1994 PCT Pub. No. WO95/03830 PCT Pub. Date Feb. 9, 1995A prodrug of the general formula FTLi-(PRT)m, where m is an integer from 1 to 5; FTLi is a ras inhibitor such as a farnesyltransferase inhibitor compound, such as Ia, Ib, Ic; and PRT represents m protecting groups or a precursor thereof, such as compound XVI, which are capable of being cleaved from the ras inhibitor by the action of a enzyme. |