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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-06
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-06
filingDate 1994-10-26^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1997-07-23^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc54edc37cae51d72920e21f5a7945dd
publicationDate 1997-07-23^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0725785-B1
titleOfInvention Process for the preparation of rufloxacin and salts thereof
abstract PCT No. PCT/EP94/03512 Sec. 371 Date Apr. 24, 1996 Sec. 102(e) Date Apr. 24, 1996 PCT Filed Oct. 26, 1994 PCT Pub. No. WO95/11907 PCT Pub. Date May 4, 1995A process for the preparation of rufloxacin, a compound of the formula I <IMAGE> and salts thereof is described. This is effected by reducing a quinoline disulfide of formula (II) as herein defined, and subjecting the resulting 2-mercaptoethyl quinoline of formula (III) as herein defined to a cyclization in a basic medium and hydrolyzing the rufloxacin ester thus obtained and, if desired, forming the salts thereof.
priorityDate 1993-10-27^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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