http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0763042-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e9445e5e3626f36e932c6451a928250 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H9-06 |
| filingDate | 1995-05-19^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0626690d3b473c8b21f6a6a8d66f17bb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0454fbd6b40f2e1663df6bbf62c3366 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbdbbb93fa5631b3a0603cf9da145315 |
| publicationDate | 1997-03-19^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-0763042-A1 |
| titleOfInvention | Polycyclic lactam derivatives for sensitizing multidrug-resistant cells to antitumour agents |
| abstract | Staurosporin derivatives of formula (I), wherein R1 is formyl, an aliphatic hydrocarbon radical having up to 29 carbon atoms that is unsubstituted or substituted by aryl, or is an aryl radical, R2 is an aliphatic, carbocyclic, carbocyclic-aliphatic, heterocyclic or heterocyclic-aliphatic radical each having up to 29 carbon atoms that is other than C1-C5alkyl, or is a heterocyclic or heterocyclic-aliphatic radical each having up to 20 carbon atoms and up to 9 hetero atoms, or is an acyl radical having up to 30 carbon atoms that is other than benzoyl, benzyloxycarbonyl, lower alkanoyl or α-aminoacyl having a free or protected amino group, and R3 is hydrogen, hydroxy, lower alkoxy or oxo, are described. These derivatives can be used for avoiding or removing multidrug resistance to antitumour agents, such as vinblastine or adriamycin. |
| priorityDate | 1994-06-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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