| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_56648a3835729246a809b1a3e2fd8117 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
1995-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2004-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_708c8ccc952c511c291885a4546e4050
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eaffe19913fbc5171114eb3a169ff1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8253ba174a8ad1bc3b8e3ad58e4434d2 |
| publicationDate |
2004-10-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-0842289-B1 |
| titleOfInvention |
Homologous recombination in mismatch repair inactivated eukaryotic cells |
| abstract |
A mammalian cell having a mismatch repair-deficient phenotype is provided, where one or both alleles of a gene essential for mismatch repair, such as an Msh gene, are inactivated. Using this cell in a gene knock-out methodology advantageously allows efficient homologous recombination, even when the DNA sequences of the donor and recipient sequences diverge by significantly more than 0.6%. |
| priorityDate |
1995-07-26^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |