| abstract |
It becomes a pathogenetic concept of insulin resistancenand the diabetes mellitus based on it.n n n The concept is based on a permeability defectnSmall intestinal mucosa that leads to inactivation of insulin receptorsnin the vascular endothelium and further to an insulin deficiency situationnleads to the target cells.n n n With different substances is targeted into the pathogenesisnthe insulin resistance intervened. Improvednso-called diabetic comorbidities. |