| abstract |
A recombinant soluble human thyroid hormone receptor,ncomprising an extracellular domain moiety of a human thyroidnhormone receptor, or a mutant thereof, being secretory, andnhaving reactivity with an anti-human thyroid stimulatingnhormone receptor autoantibody; a composition for assaying annanti-human thyroid stimulating hormone receptor antibody,ncomprising the receptor and a carrier or diluent; a methodnfor assaying an anti-human thyroid stimulating hormonenreceptor antibody, comprising reacting an anti-human thyroidnstimulating hormone receptor antibody with the receptor; andna process for producing a recombinant soluble human thyroidnhormone receptor which is secretory and has reactivity withnan anti-human thyroid stimulating hormone receptornautoantibody, comprising infecting an insect cell with anrecombinant baculovirus introduced with an extracellularndomain moiety of a gene encoding a human thyroid hormonenreceptor or a mutant thereof, and culturing the infected cell. |