http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1089759-A1

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filingDate 1999-06-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e35229b1c886d439d399b411a83419e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27781e31f58ea0fbabcc0abf652de1f7
publicationDate 2001-04-11^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1089759-A1
titleOfInvention Synthetic peptide vaccines for foot-and-mouth disease
abstract The present invention relates to the use of a peptide composition as an immunogen, with each peptide contained therein comprising a target antigenic site derived from the VP1 capsid protein of Foot-and-Mouth Disease Virus (FMDV). The antigenic site is covalently linked to a helper T cell epitope and, preferably, to other immunostimulatory sequences, preferably by conventional peptide bond(s) through direct synthesis, for the prevention of FMDV infection and eradication of Food-and-Mouth Disease (FMD). More particularly, the present invention relates to the use of such peptide composition as an immunogen to elicit the production in animals including swine, cattle, sheep, goets and susceptible wild species, of high titer polyclonal antibodies that can effectively neutralize, in vitro, multiple strains or serotypes of FMDV, and to the use of such composition as a vaccine to prevent, and/or reduce the incidence of, FMDV infection regardless of serotype, and thus affect the eradication of FMD. The present invention also relates to the peptides used in the compositions, and to immunoassays and/or diagnostic kits containing one or more of these peptides, and methods of diagnosing FMDV in mammals using such materials.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102175852-A
priorityDate 1998-06-20^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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