http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1118611-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_324beb8b942a3a6ed1f1f576bcd76c45 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-20 |
| filingDate | 1999-09-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48e24e8158f4dec3bb5e2525faa5ba18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46dd79b3f873a763d04e64a8e40945b4 |
| publicationDate | 2001-07-25^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1118611-A1 |
| titleOfInvention | Process for the preparation of oxazolidinone derivative |
| abstract | The invention relates to a process for preparingn(5RS)-5-benzyl-3-[(1SR)-3-morpholino-1-phenylpropyl]-1,3-oxazolidin-2-onenor its pharmacologically acceptable saltnwhich is of value as a remedy for treatment of incontinencenof urine and thamuria and which is performed by thensteps of:n dissolving an acid and a mixture of (2RS)-1- [(1SR)-3-morpholino-1-phenylpropyl]amino-3-phenyl-2-propanolnandn(2RS) -1- ((lRS,) -3-morpholino-1-phenylpropyl] amino-3-phenyl-2-propanolnin a solvent to obtain a salt of the formern(1SR)-compound utilizing difference of solubilitynbetween the salt of (1SR)-compound and a salt of thenlatter (1RS)-compound; bringing a basic compound into contact with the saltnof (1SR)-compound to produce a free (1SR)-compound; reacting thus produced (2RS)-1-[(1SR)-3-morpholino-1-phenylpropyl]amino-3-phenyl-2-propanolnwith a compoundnhaving the formula (I):n R 2 C=O nwherein R represents a chlorine atom, an alkoxy group, annaryloxy group or an amino group,nor a chloroformic acid ester; and cyclizing the resulting product. |
| priorityDate | 1998-10-01^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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