http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1123095-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd47318319f20f7f99d9fef1fd3e511b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 |
| filingDate | 1999-10-15^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ddf2a192450ddd09143e8bb79beeb0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e81fd406af0570b4c869ecf313f8fb16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5e32e68bf4df31b48741d47fe7e2510e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c871e40f98a400627ef3309614ff55a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff8045586c9e617dfd4b666801c2e1ce |
| publicationDate | 2001-08-16^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1123095-A1 |
| titleOfInvention | Pharmaceutical formulations useful to treat inflammatory and immune disorders |
| abstract | A pharmaceutical formulation is provided for the treatment of inflammatory and/or immune disorders, particularly those mediated by platelet activating factor ('PAF') or a product of 5-lipoxygenase. The formulation, in one embodiment, is an essentially anhydrous ointment containing an active agent selected from the group consisting of 2,5-diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines, and an enhancer composition containing one or more C3-18 esters such as diethyl succinate, propylene carbonate, diisopropyl adipate and glyceryl triacetate. In another embodiment, the formulation is a cream, gel, lotion, oil, or the like, containing the active agent in crystalline form. The invention also encompasses the novel crystalline form of the active agent, and methods for using the formulations to treat individuals with inflammatory and/or immune disorders. Also encompassed is use of isopropyl alcohol (IPA) to enhance stability of the active agent and pharmaceutical formulations. |
| priorityDate | 1998-10-16^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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