| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07addebfc9446dc5a9a77692ebf4dac1 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0028
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0057 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-483
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate |
2000-04-26^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f1400e7009c4dcb051437bf54640b400
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_701248abf199a5cd415427d42645cc44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_202805e68eca6511b043fc3d3c8f9c01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d37ee1c739098b23d893a5c2c7f16283 |
| publicationDate |
2002-02-13^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1178830-A2 |
| titleOfInvention |
Cyanine and indocyanine dye bioconjugates for biomedical applications |
| abstract |
Dye-peptide conjugates useful for diagnostic imaging and therapy are disclosed. The dye-peptide conjugates include several cyanine dyes with a variety of bis- and tetrakis (carboxylic acid) homologues. The small size of the compounds allows more favorable delivery to tumor cells as compared to larger molecular weight imaging agents. The various dyes are useful over the range of 350-1300 nm, the exact range being dependent upon the particular dye. Use of dimethylsulfoxide helps to maintain the fluorescence of the compounds. The molecules of the invention are useful for diagnostic imaging and therapy, in endoscopic applications for the detection of tumors and other abnormalities and for localized therapy, for photoacoustic tumor imaging, detection and therapy, and for sonofluorescence tumor imaging, detection and therapy. |
| priorityDate |
1999-05-20^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |