| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6c8d4dc7bd1a30d8fda907fceaeb4e69 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-416
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-20 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-40 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-416
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate |
2001-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f444cc3ada26282f39d949ed5178d34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f65e36062bb8c791c6d9cddcda561657
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027bb2a0808a0e61154c649d67ac2e9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd9a6a57246aa6b548e0234b830f46ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ed555dec8d994a937bf42dc68ed2388 |
| publicationDate |
2002-03-20^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-1188744-A1 |
| titleOfInvention |
Process for producing 1H-3-aminopyrrolidine and derivatives thereof |
| abstract |
A process for producing 1H-3-aminopyrrolidine and derivatives thereof isndisclosed. The process is especially useful for producing optically active 1H-3-aminopyrrolidinenand derivatives thereof and in this case comprises reacting annoptically active amino-protected aspartic anhydride represented by the formula (1)nwith a primary amine represented by the formula R'NH 2 , subjecting the reactionnproduct to cyclodehydration to obtain an optically active 1-aralkyl-3-(protectednamino)pyrrolidine-2,5-dione compound represented by the formula (2), subsequentlyneliminating the protective group from the 3-position amino group of the compoundnrepresented by the formula (2) to obtain an optically active 1-aralkyl-3-aminopyrrolidine-2,5-dionencompound represented by the formula (3), reducing thencarbonyl groups of the compound represented by the formula (3) to obtain either annoptically active 1-aralkyl-3-aminopyrrolidine compound represented by the formulan(4) or a salt thereof with a protonic acid, and then subjecting the compoundnrepresented by the formula (4) or the salt thereof to hydrogenolysis to obtain annoptically active 1H-3-aminopyrrolidine or a protonic acid salt thereof. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-101955457-A |
| priorityDate |
2000-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |