http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1200434-B1
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d12b35c0dd9adfb167b3b4f383afe93 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2000-07-27^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2003-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c018f39a92bdbe37fb2d52e5df429685 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f638c0e542dddc0b5d395b9b9ed255a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f931ed976eab98747d76d5f015d90c36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49cead54f5da6b7c889acc4500c08bf8 |
publicationDate | 2003-05-14^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1200434-B1 |
titleOfInvention | NEW CYTOTOXIC PYRIDO 2,3,4-kl]ACRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE |
abstract | The invention provides compounds of formula (I)whereinR1 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms, a hydroxy group, an alkoxy group having from 1 to 6 carbon atoms, a halogen atom, a nitro group, an amino group, a monoalkylamino group wherein the alkyl moiety has from 1 to 6 carbon atoms, a dialkylamino group wherein each alkyl moiety may be the same or different and each has from 1 to 6 carbon atoms, a dialkoxyamino group wherein each alkoxy moiety may be the same or different and each has from 1 to 6 carbon atoms, an alkanoyalmino group having from 1 to 20 carbon atoms or an alkanesulfonylamino group having from 1 to 6 carbon atoms;R2 represents a hydrogen atom or an alkyl group having from 1 to 6 carbon atoms; andR3 represents a hydrogen atom, an alkyl group having from 1 to 6 carbon atoms or an alkoxy group having from 1 to 6 carbon atoms;and pharmaceutically acceptable salts thereof. The compounds exhibit activity against a wide variety of mammalian cancer cell lines. |
priorityDate | 1999-07-30^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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