http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1233828-A2
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4483b7dcfa169d7ea8a61300461c0b4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-40 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0237 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-74 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-74 |
filingDate | 2000-11-30^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9601ecca8014c70f65b7843cf07f6e80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3bcc8f49814b470ba41c8c013e4c90 |
publicationDate | 2002-08-28^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | EP-1233828-A2 |
titleOfInvention | Chiral catalysts for asymmetric acylation and related transformations |
abstract | A chiral catalyst comprising a 3, 4-disubstituted pyridine, or a salt, N functionalised derivative, dimer or oligomer thereof, wherein the 3-substituent is substantially hindered from rotation about the bond (sp<SUP>2</SUP>-sp<SUP>2 </SUP>biaryl axis) linking it to pyridine and the 4-substituent is an aliphatic or aromatic amine linked by a single bond to the pyridine, the pyridine nitrogen being functionalised or unfunctionalised, preferably comprising a compound of formula I wherein Z is a group substantially hindered from rotation about its bond; and each of R<SUP>1 </SUP>and R<SUP>2 </SUP>are independently selected from C<SUB>1-30 </SUB>alkyl, C<SUB>3-30 </SUB>cyclo alkyl and/or C<SUB>3-30 </SUB>aryl, or NR<SUP>1 </SUP>R<SUP>2 </SUP>form a cyclic amine; wherein R<SUP>1 </SUP>and/or R<SUP>2 </SUP>may be optionally substituted and/or include one or more heteroatoms; a composition or support comprising the catalyst; process for the preparation and resolution thereof; process for stereoselective reaction of an optically inactive substrate using the catalyst; and the optically active reaction product thereof. |
priorityDate | 1999-11-30^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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