Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4625ca7b4dbee128c88cd85dfc84f896 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2202-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2202-22 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0035 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00 |
filingDate |
2001-05-16^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb97f36cdd1932cb8c9601556d00d0b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b188f9731b90b5e964580bb73e8a7807 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70b2a81a0958ecd40a35e510cf9e09a0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aabd4936d464bb1760d6908851ec587 |
publicationDate |
2003-03-05^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1286706-A2 |
titleOfInvention |
Gamma irradiation of protein-based pharmaceutical products |
abstract |
Methods are disclosed for inactivation of microbial contaminants in proteinaceous materials while preserving the activity of the materials. The proteinaceous material is exposed to gamma radiation at a high dose rate (e.g., ⊃ 3 kiloGray/hour) while in a lyophilized state under conditions which preserve activity of the material. The material may be formulated to contain one or more stabilizers, and/or be lyophlized to a low moisture content (e.g., less than 1.5%) prior to exposure to the gamma radiation. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11740019-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11747082-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11604026-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609042-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11609043-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11634257-B2 |
priorityDate |
2000-05-17^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |