Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c08da811c7cf1a6e666e94482fb29a9a |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-102 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 |
filingDate |
2001-11-07^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2011-08-03^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cba2bd6c9c7358fefda3305e99a1ab1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9877a74a99e23bfe08017b3f1b97e77f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e197f88829796c6e309497d0e1b3bee6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58d1083c8b1273d0f65d7c4e0d962eaf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7fbf99b0837833dddcf5911c32c48f5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6307ab42a2218067562d2dd4300d99ad |
publicationDate |
2011-08-03^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-1332210-B1 |
titleOfInvention |
Use of mutagenic dna polymerase for producing random mutations |
abstract |
The invention concerns a method for random mutagenesis comprising the replication of a DNA sequence in the presence of an efficient amount of at least a mutase, for example a Pol β, the random mutagenesis rate being at least of the order of 1 mutation for 400 base pairs. The replication product, optionally recombined and amplified, is cloned in an expression vector so as to generate mutated polypeptides which will be selected on the basis of the desired property or properties. |
priorityDate |
2000-11-08^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |