| abstract |
The invention relates to novel pyrazolopyridine derivatives of the formula (I), wherein R1 represents hydrogen or a di-C¿1-6?-alkylaminocarbonyl group, R?2¿ represents a rest of the formula -O-CO-NR3R4, wherein R?3 and R4¿ are the same or different and represent a rest of the group comprising optionally substituted C¿1-6 ?alkyl, optionally substituted C2-6 alkenyl, or optionally substituted C3-8 cycloalkyl; or which, together with the nitrogen atom to which they are bound, form a five- to seven-membered saturated heterocycle that may optionally contain an additional hetero atom from the group N, O, S and/or that may be optionally substituted, and to the salts, isomers and hydrates of said derivatives, as stimulants of the soluble guanylate cyclase and for use as agents for treating cardiovascular diseases, hypertonia, thromboembolic diseases and ischemia, sexual dysfunction or inflammations, and for treating diseases of the central nervous system. |