abstract |
A quality control method of a DNA microarray is provided which includesnpreparing a DNA spotting solution containing a first fluorescent dye having particularnexcitation and emission wavelengths, applying the DNA spotting solution to ansubstrate of a DNA chip to form DNA spots in which the first fluorescent dye is boundnto the substrate, and detecting fluorescent signals from the DNA spots. In the DNAnmicroarray quality control method, since a signal from a fluorescent dye covalentlynbound to the solid chip surface together with DNA probe is used for the qualityncontrol, staining and dye-removing processes, which were performed in conventionalnquality control methods, are unnecessary. |