| abstract |
Compounds of the formula (I) in which R1 is CN, or C(=NH)-NH¿2?, CON(R?3)¿2 or [C(R4)2]nN(R3)2, each of which is unsubstituted or monosubstituted by C(=O)R?3, COOR3, or3¿ or by a conventional amino-protecting group, or W is -NR3CO-, -NR?3COC(R4)¿2, NR3C(R4)¿2) or -C(R4)2NR3C(R4)2-, X is -C(R3)2-, -[C(R3)2]2-, -C(R3)2O- or -C(R3)2NR3, Y is alkylene, cycloalkylene, Het-diyl or Ar-diyl, T is OR?3, N(R3)¿2, N(R3)2CON(R3)2, a monocyclic or bicyclic, saturated, unsaturated or aromatic heterocyclic radical having from 1 to 4 N, O and/sor S atoms which is unsubstituted or monosubstituted, disubstituted or trisubstituted, or a phenyl radical which is unsubstituted or monosubstituted, disubstituted or trisubstituted are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic disorders and for the treatment of tumours. |