http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1370652-A2

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5098eff6d67391cd857fae0aa3174bcb
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1058
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
filingDate 2002-03-12^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92741363a0c968ebe934e1363045a822
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5864838e12bee5d64bd8b8d6b1a5d9a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34af892f63734dde0faa6349e1232dc9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_10a4d34c6c2d0821230322ccc8bffcdd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_895a7c9b5a8df997679e078bb4dba333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cc84f486aea2201fb741bf1d158e2e9
publicationDate 2003-12-17^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-1370652-A2
titleOfInvention Screening method comprising combination of discrete dimension assay testing of actives, gene mutation and application assay testing of selected actives
abstract The present invention relates to a screening method for identifying actives (peptides or proteins) with improved performance comprising: (1) screening a library of actives encoded by nucleotide sequences in at least two different discrete dimension assays employing selected parameters and selecting the actives exhibiting improved properties in the discrete dimension assays, (2) collecting nucleotide sequences encoding the selected actives, (3) mutating collected nucleotide sequences, (4) screening actives encoded by the mutated nucleotide sequences in an application assay and selecting actives, which exhibit improved performance.
priorityDate 2001-03-12^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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