http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1377678-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4e69a456f4fcac792f8f7d7b967b4b2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-567 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2001-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c94f056d7176372aaf07202d1356237 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f50fc230bc8ae031ff282e1481463761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5983958b3caa6a3c506adad636657c3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac660732e537080a33e69d9a4694ba22 |
| publicationDate | 2004-01-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1377678-A2 |
| titleOfInvention | Diagnostic and therapeutic use of a caveolae-associated integral membrane protein for alzheimer's disease and related neurodegenerative disorders |
| abstract | The present invention discloses the differential expression of the caveolae-associated integral membrane protein flotillin-1 gene in specific brain regions of Alzheimer s disease patients. Based on this finding, this invention provides a method for diagnosing or prognosing Alzheimer s disease or other neurodegenerative diseases in a patient, or for determining whether a subject is at increased risk of developing Alzheimer s disease or other related neurodegenerative diseases. Furthermore, this invention provides therapeutic and prophylatic methods for treating or preventing Alzheimer s disease and related neurodegenerative disorders using a caveolae-associated integral membrane protein gene, in particular the flotillin-1 gene. A method of screening for modulating agents of neurodegenerative diseases is also disclosed. |
| priorityDate | 2000-08-24^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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