abstract |
The present invention relates to a method for preparing (3S,4R)-trans-4-(4-fluorophenyl)-3-hydroxymethylpiperidinenrepresented by the formula (II):n nThe method comprises the step of optically resolving (3SR,4RS)-trans-4-(4-fluorophenyl)-3-hydroxymethylpiperidinenwith o-chlorotartranilic acid as an opticallynactive organic acid. |