http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1480927-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42f95534457c954d02cb5dc0834b8b9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_753c0e36e3801d4916536a65a77efc35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_abb1180711680dd7b3431f6f21ebaae5 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate | 2003-03-04^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b4d8c1bfd5ce3407cfa8ec8c0c7a46b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf23542ce62e2577ac9f7ea1324cb781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36e75558e710bc7678ad6b384918ed7d |
| publicationDate | 2004-12-01^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-1480927-A2 |
| titleOfInvention | A method for cleavage of labile functional groups from chemical compounds |
| abstract | The present invention provides a method for cleavage of labile functional groups from molecules by the action of electromagnetic radiation, wherein the molecules are contacted with a chemical compound whose triplet state is energetically higher than the triplet state of the labile functional group, and are subsequently exposed to electromagnetic radiation. Further, the invention provides a method for preparing DNA chips by spatially addressed, light-controlled nucleotide synthesis on solid substrates, said method comprising the following steps: a) reacting the unprotected terminal 3' or 5' hydroxy group of a nucleoside and/or of a nucleotide arranged on the solid substrate under usual conditions with a photolabile protective group and optionally purifying the reaction product, b) applying a solution, suspension or dispersion of a chemical compound, whose triplet state is energetically higher than the triplet state of the photolabile protective group, to the surface of the carrier, said surface comprising the nucleotides and/or nucleosides modified in step a); c) irradiating, in a spatially selective manner, the surface of the carrier treated in step b) with electromagnetic radiation in the UV/VIS range with simultaneous, spatially selective release of a reactive OH group and subsequently reacting it with a nucleoside and/or nucleotide comprising a 5' or 3'OH group, said nucleoside and/or nucleotide being further provided with a photolabile functional group. Moreover, the present invention provides a chemical composition comprising a molecule having a labile functional group, as well as a chemical compound whose triplet state is higher than the triplet state of the labile functional group, and it describes the use of the chemical composition for preparing DNA chips. |
| priorityDate | 2002-03-04^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Showing number of triples: 1 to 198 of 198.